Calculate Phenotype Risk Scores • phers

phers is an R package for calculating phenotype risk scores, which quantify the extent to which a person’s clinical diagnoses resemble a given Mendelian disease. For details on the R package, see Aref et al. (2022). For details on the original application of phenotype risk scores, see Bastarache et al. (2018).

Installation

Option 1: CRAN

install.packages('phers')

Option 2: Hughey Lab Drat Repository

Install BiocManager.

if (!requireNamespace('BiocManager', quietly = TRUE))
  install.packages('BiocManager')

If you use RStudio, go to Tools → Global Options… → Packages → Add… (under Secondary repositories), then enter:
- Name: hugheylab
- Url: https://hugheylab.github.io/drat/
You only have to do this once. Then you can install or update the package by entering:
```
BiocManager::install('phers')
```
Alternatively, you can install or update the package by entering:
```
BiocManager::install('phers', site_repository = 'https://hugheylab.github.io/drat/')
```

Usage

Check out the reference documentation.